Product ID:M-TOLUNITRILE, 218672
MSDS Date:01/26/1994
FSC:6810
NIIN:00N055245
MSDS Number: CDMZZ

ICN BIOMEDICALS

1263 S CHILLICOTHE RD
AURORA, OH 44202
US

Emergency Phone: 800-424-9300 (CHEMTREC)

Info Phone: 216-562-1500

Preparer: RL

Cage: IO030

ICN BIOMEDICALS INC

28050 CLEVELAND, OH 44128-0250 US

Telephone: 216-831-3000

Cage: IO030

M-TOLUNITRILE; (3-CYANOTOLUENE)

CAS: 620-22-4

RTECS: XV0525000

OSHA PEL N/K

ACGIH TLV: N/K

PEACH & SIMILAR FRUIT PITS & IN SWEET

RTECS: 9999999ZZ

BENZALDEHYDE, & CYANIDE FROM WHICH THE LATTER CAN BE

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THESE ENZYMES ARE NOT FOUND IN MAMMALIAN TISS, THE

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SIMILAR ENZYMES CAPABLE OF EFFECTING CYANIDE RELEASE

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BE AS MUCH AS 40 TIMES MORE TOX BY ORAL RTE AS

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ING OF LAETRILE, & THIS ALLEGED ANTICANCER DRUG HAS

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ETHICAL DRUG THAT MAY ALSO CAUSE CYANIDE POIS IN

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SODIUM NITROPRUSSIDE. ALTHOUGH NITROPRUSSIDE IS

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PENETRATES INTO ERYTHROCYTES & REACTS W/HEMOGLOBIN

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FORTUNATELY, THE THERAPEUTIC MARGIN FOR

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FOUND IN CERTAIN RAT & PEST POIS, SILVER & METAL

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CMPDS SUCH AS POTASSIUM CYANIDE CAN ALSO BE READILY

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ABSORBED FROM ALL RTES, INCL SKIN, MUC MEMB, & BY

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WHEN INGESTED. DEATH MAY OCCUR W/INGEST OF EVEN SML

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MIN/HRS DEPENDING ON RTE OF EXPOS. INHAL OF TOX

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EXPOS. SODIUM NITROPRUSSIDE (SMITH & KRUSZYNA,

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ALSO CAUSED CYANIDE POIS. A BLOOD CYANIDE LEVEL OF

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USUALLY HAD LEVELS > 1 UG/ML. CLINICALLY, CYANIDE

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BRTH OF PATIENT; HOWEVER, ONLY SML PROPORTION OF

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ODOR. TYPICALLY, CYANIDE HAS A BITTER, BURNING

RTECS: 9999999ZZ

VOMIT, ANXIETY, CONFUSN, VERTIGO, GIDD, LOWER JAW

RTECS: 9999999ZZ

ARRHY, & TRANSIENT RESP STIMULATION FOLLOWED BY

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BUT IN MOST CASES HEARTBEAT USUALLY OUTLASTS RESP

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CONSIDERED TO BE CHARACT OF CYANIDE POISONING. FOR

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LD50 LC50 Mixture:LD50 (ORAL RAT): 4200 MG/KG.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE/CHRONIC:MILDLY TOX BY INGEST.
SEV EYE IRRIT. CYANIDE DIRECTLY STIMULATES CHEMORECEPTORS OF
CAROTID & AORTIC BODIES W/RESULTANT HYPERPNEA. CARD IRREGS ARE
OFTEN NOTED, BUT HEART INVARIABLY OUTLAS TS RESPS. DEATH IS DUE TO
RESP ARREST OF CENTRAL ORIGIN. IT CAN OCCUR W/IN SECS/MIN OF INHAL
OF HIGH (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT.
Effects of Overexposure:HLTH HAZ:CONCS OF HYDROGEN CYANIDE GAS. BECAUSE
OF SLOWER ABSORPTION, DEATH MAY BE MORE DELAYED AFTER INGEST OF
CYANIDE SALTS, BUT CRITICAL EVENTS STILL OCCUR W/IN FIRST HR. TWO
OTHER SOURCES OF CYANI DE HAVE BEEN RESPONSIBLE FOR HUMAN POIS. ONE
OF THESE IS AMYGDALIN, A CYANOGENIC GLYCOSIDE FOUND IN APRICOT,
(ING 2)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:SKIN: REMOVE CONTAM CLTHG, RINSE LIBERALLY W/SOAP & WATER FOR
CONSIDERABLE PERIOD. CALL MD. INGEST: RINSE MOUTH SEVERAL TIMES
W/WATER, DO NOT SWALLOW. CALL MD/TAKE PATIENT TO HOSPITAL. EYES:
RINSE LIB ERALLY W/WATER FOR CONSIDERABLE PERIOD (AT LEAST 15 MIN).
CALL MD/TAKE PATIENT TO HOSPITAL. INHAL: TAKE PATIENT INTO FRESH
AIR & ALLOW TO REST. CALL MD/TAKE PATIENT TO HOSPITAL.

Flash Point:188F,87C
Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL, FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SCBA & FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:MOD, BY CHEM RXN W/HEAT, MOISTURE, ACID.
MANY CYANIDES EVOLVE HYDROCYANIC ACID RATHER EASILY. THIS IS A FLAM
GAS & IS HIGHLY TOX. CARBON DIOXIDE FROM (SUP DAT)

Spill Release Procedures:ABSORB THE LIQUID IN DRY SAND, DIATOMITE,
VERMICULITE, ETC, SHOVEL THE MIXTURE INTO PLASTIC BAGS AND REMOVE
TO THE CENTRAL DEPOT FOR CHEMICAL WASTE. SWEEP INTO SUITABLE
CONTAINER FOR DISPOSAL.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:ALWAYS WEAR GLOVES, MASK, GOGGLES AND
USE A HOOD. STORE AT ROOM TEMPERATURE.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:YES. USE NIOSH APPROVED RESPIRATOR APPROPRIATE
FOR EXPOSURE OF CONCERN .
Ventilation:LOCAL EXHAUST REQUIRED.
Protective Gloves:YES. IMPERVIOUS GLOVES .
Eye Protection:ANSI APPRVD CHEM WORKERS GOGGLES .
Other Protective Equipment:EMERGENCY EYEWASH AND DELUGE SHOWER MEETING
ANSI DESIGN CRITERIA .
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
EXPLO HAZ: AIR IS SUFFICIENTLY ACIDIC TO LIBERATE HYDROCYANIC ACID FROM
CYANIDE SOLNS. EXPLODES IF MELTED W/NITRATE/CHLORATE @ ABOUT 450C.
VIOLENT RXN W/F*2, MG, NITRATES, HNO*3, NITRITES. DANGEROUS; ON
CONT W/ACID, ACID FUMES, WATER/STEAM, THEY WILL PRDCE TOX & FLAM
VAPS.

Boiling Pt:B.P. Text:>89F,>32C
Melt/Freeze Pt:M.P/F.P Text:-9F,-23C
Spec Gravity:0.976
Solubility in Water:INSOLUBLE
Appearance and Odor:COLORLESS LIQUID

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:TOXIC FUMES OF CN-, NO*X.

Waste Disposal Methods:INCINERATE OR LANDFILL AS COMPLIES WITH STATE
AND LOCAL LAWS. DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE AND
FEDERAL REGULATIONS .

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.